Angiopoietin 2 anticorps (Middle Region)

N° du produit ABIN2789397

Cet anticorps anti-Angiopoietin 2 est un anticorps Lapin Polyclonal détectant Angiopoietin 2 dans WB. Adapté pour Humain, Souris, Rat, Porc, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval et Mouton.

Aperçu rapide pour Angiopoietin 2 anticorps (Middle Region) (ABIN2789397)

Antigène: Angiopoietin 2 (ANGPT2)

Reactivité: Humain, Souris, Rat, Porc, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Angiopoietin 2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Angiopoietin 2 anticorps

Épitope: Middle Region

Séquence: NQTTRLELQL LQHSISTNKL EKQILDQTSE INKLQNKNSF LEQKVLDMEG

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%

Attributs du produit: This is a rabbit polyclonal antibody against Angpt2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Mouse Angpt2

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Angiopoietin 2

Antigène: Angiopoietin 2 (ANGPT2)

Autre désignation: Angpt2

Sujet: Angpt2 binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. It can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
Alias Symbols: Agpt2, Ang-2, Ang2
Protein Size: 496

Poids moléculaire: 56 kDa

ID gène: 11601

NCBI Accession: NM_007426, NP_031452

UniProt: O35608

Pathways: Signalisation RTK